Use the following steps to mute Window-Eyes automatically while the focus is on SpeakOn.
Start SpeakOn.
While SpeakOn has the focus, press Control + backslash to bring up the Window-Eyes control panel.
Press Alt + f to open the File menu and arrow to or press o to get to the Open sub-menu.
Press s or arrow to get to the Set file item.
When the Set file list appears, press s or arrow to the item that says, silent.000.
Press Alt + f to bring up the file menu, then press Save as.
Accept the default name which is speakon.000.
After pressing Enter, a dialogue box will pop up asking you to confirm the association.
Say "Yes", and this will associate Window-Eyes with SpeakOn.
Thanks to Mike Reiser for the above information.
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